TP53 and neoplasm: Also, molecular analyses are worth consideration as additional criteria;they are helpful but not obligatory for confirming the diagnosis of NIFTP, as they candetermine the presence of the BRAFV600E mutation, as well asother high-risk mutations (e.g., of TERT or TP53), and ifthese mutations are present, the tumor can still be classified as NIFTP, but in these casesintensified search for invasive features and papillae should be triggered [10].