Further studies are warranted on whetherbleomycin would suppress the growth of other PDAC cell lines (both in vitroand in vivo), whether it indeed binds to FN1 and/or Serpin B5, how itregulates the biological functions of these two proteins in both PDAC cells and tumor ECM,and whether it can inhibit DNA synthesis in PDAC. Here, FN1 is linked to neoplasm.