In this study, we classified ALI patients into two groups by serum ALT/LDH ratio; the low ALT/LDH ratio and high ALT/LDH ratio groups, and found upregulated FDP and PT-INR and sinusoidal fibrin deposition in the low ALT/LDH ratio group relative to the high ALT/LDH ratio group. The gene discussed is GPT; the disease is acute respiratory distress syndrome.