According to these criteria, 4 candidate genes were selected from the top up-regulated genes in peritoneal metastasis compared to primary gastric cancer, which were S100A13 (S100 calcium-binding protein A13), BCHE (Butyrylcholinesterase), ITGA4 (Integrin alpha 4) and LIMK1 (LIM domain kinase 1) (Fig. 1D). This evidence concerns the gene BCHE and gastric cancer.