Moreover, we recognised the positive correlation between the expression of ALKBH4 and E2F1, as well as between that of ALKBH4 and of each of the E2F1-target genes, regardless of the histologic subtypes, using TCGA database (Supplementary Fig. S6A,B) in NSCLC. The gene discussed is ALKBH4; the disease is non-small cell lung carcinoma.