Interestingly, the SERPINA1 locus also anchors genetic variants related to CHD [20], and other identified loci present with genetic variants associated with body mass index (DNMT3A, ABTB2, ZBTB16, NISCH, AHRR, DLEU1), inflammatory biomarkers or blood cell counts (AIM2, ITPKB, DNMT3A, LZTFL1, PSMB7, ZBTB16, ACTN1, SERPINA1, MPO, DNAJC5B, CPM, DLEU1, ZFPM1), blood pressure (PTCD2, PSMB7, SERPINA1, AHRR) and lipids (SERPINA1, NISCH, DLEU1, ZFPM1) [21]. The gene discussed is LZTFL1; the disease is coronary artery disorder.