Given that the cytokines interleukin-1 alpha (IL-1α) and beta (IL-1β) are implicated in RP etiology [2, 4], rilonacept, an IL-1 α and IL-1 β cytokine trap, was evaluated in clinical trials for the treatment of RP [5, 6] and is now the first treatment approved by FDA for RP. The gene discussed is IL1B; the disease is retinitis pigmentosa 1.