CD68 and neoplasm: Multivariable Cox regression analysis revealed that high CD68+ cell density was not associated with OS (HR = 1.68, 95%CI 0.48–22.8, p = 0.2), while high tumor/CD68+ clustering was associated with significantly worse OS (HR = 6.19, 95%CI 1.16–33.1, p = 0.033) (Fig 3C).