LRRK2 and Parkinson disease: The estimated (SE) rates of worsening in MDS-UPDRS III scores were 1.15 (0.16) points/y for idiopathic PD, 1.64 (0.26) points/y for GBA PD, 0.87 ± 0.20) points/y for LRRK2 PD, and 1.00 (0.35) points/y for LRRK2/GBA PD.