BTK and myeloid sarcoma: As BTK inhibitors dampen B cell function, four BTK inhibitors are currently tested in phase I, II, or III clinical trials for the treatment of MS: evobrutinib (M2951, MSC2364447), tolebrutinib (PRN-2246, SAR442168), fenebrutinib (BDC-0853, RG7845), and BIIB091.