Additionally, a total of 170 enriched KEGG pathways (adjusted, P < 0.05) were obtained, the top 10 including AGE-RAGE signaling pathway in diabetic complications (hsa04933), Kaposi sarcoma-associated herpesvirus infection (hsa05167), fluid shear stress and atherosclerosis (hsa05418), hepatitis B (hsa05161), prostate cancer (hsa05215), hepatitis C (hsa05160), pancreatic cancer (hsa05212), human cytomegalovirus infection (hsa05163), IL-17 signaling pathway (hsa04657), and TNF signaling pathway (hsa04668). This evidence concerns the gene TNF and Familial prostate cancer.