Based on the adjusted P value from small to large, the top 10 KEGG pathways were mainly enriched in AGE-RAGE signaling pathway in diabetic complications, Kaposi sarcoma-associated herpesvirus infection, fluid shear stress, and atherosclerosis, hepatitis B, prostate cancer, hepatitis C, pancreatic cancer, human cytomegalovirus infection, and IL-17 signaling pathway. The gene discussed is RENBP; the disease is atherosclerosis.