CD4 and infection: Based on their relative proportions and differential abundance testing (FDR 10%), we found activated CD4+ T cells expressing IL22, circulating follicular helper T (TFH) cells, type 1 helper T (TH1) cells, CD8+ effector memory T (TEM) cells and MAIT cells relatively enriched in individuals with asymptomatic and mild infection, with NKT, proliferating CD8+ and CD4+, and CD8+ terminal effector T (TTE) cells enriched in individuals with more severe infection (Fig. 3e and Extended Data Fig. 5a,b).