Mycobacterium tuberculosis (Mtb) belongs to intracellular parasitic bacteria, and cellular immunity mediated by macrophages and T lymphocytes plays a major role in the fight against Mtb infection.[41,42] In this report, Patient 2 was classified as XLT, a relatively mild phenotype in patients with pathogenic WAS gene mutations. This evidence concerns the gene WAS and thrombocytopenia 1.