While rs593742 was found to overlap with the LIPC region, no evidence of LD between the HDL-related rs1532085 SNP nor the AD-related rs593742 specifically was observed, and there was no evidence of overlap between rs1532085 LD SNPs and ADAM10—indicating independence of this region (https://www.ncbi.nlm.nih.gov/gene). This evidence concerns the gene ADAM10 and Alzheimer disease.