Areas under receiver operating characteristic curves (AUROCCs) on the day of sepsis diagnosis according to the blinded EAC were similar for all three biomarkers {PSP, 0.75 [95% confidence interval (CI) 0.67–0.82]; CRP, 0.77 [95% CI 0.69–0.84] PCT, 0.75 [95% CI 0.68–0.83]} (Table 3 and Additional file 3: Figure 2). This evidence concerns the gene REG1A and Sepsis.