In addition, point-of-care measurement of CRP and PCT is not common in ICU, while PSP can be measured with a ‘point-of-care’ device within 5 min using a single drop of whole blood [16], leading the way for simple, on-demand, around-the-clock, serial biomarker assessments instead of one-off measurements upon the clinical suspicion of sepsis. Here, CRP is linked to Sepsis.