SNRPD1 and breast cancer: We analyzed the transcriptomic profiles of the 7 core Sm proteins across 31 cancer types and among breast cancer subtypes, and found that SNRPD1 had the highest number of cancers with over 2 folds up-regulation between cancer and normal tissues (Table 1), and the distribution of SNPRD1 could be nicely split into two sub-distributions by TNBC and non-TNBC while the other genes did not (Fig. 1a).