This does not exclude the possible existence of a cross-talk between SNRPD1 and other ribosome binding proteins such as SF3B1, SF3B2, RPL5, ARCN1, EIF3B, RAN, COPB1, RPL14, VCP, HSPE1, SNRNP200, SARS, EEF2, RPL37, CCT3, KPNB1, RPL23 that have been reported essential for breast cancer survival besides SNRPD1 [14]. The gene discussed is COPB1; the disease is breast carcinoma.