MGAT5 and chronic obstructive pulmonary disease: However, the A allele of rs6430491near MGAT5 (OR 0.69, 95% CI 0.55–0.87, p = 0.002) and the G allele of MGAT5-rs2593704 (OR 0.74, 95% CI 0.57–0.95, p = 0.020) were correlated to reduced risk of COPD.