INPP4B and neoplasm: These findings seem to be consistent with the report by Yang et al., which revealed that INPP4B plays a tumour suppressor role in non-metastatic colorectal cancer stem-like cells (CR-CSLCs) and plays an oncogene role in metastatic CR-CSLCs according to different mechanisms, although INPP4B is weakly expressed in non-metastatic CR-CSLCs and highly expressed in metastatic CR-CSLCs [32].