In detail, 9 CpG sites of DCN, 1 CpG site of CCL12, 2 CpG sites of IGJ, 16 CpG sites of SFRP4, 13 CpG sites of MOXD1, 11 CpG sites of CXCL14, 18 CpG sites of STMN2, 7 CpG sites of FCN3, 22 CpG sites of COMP, 33 CpG sites of LAMA2, 4 CpG sites of CPA3, and 18 CpG sites of NPY1R were found significantly differently methylated in HCC, compared with normal samples (Supplementary Table 4). The gene discussed is LAMA2; the disease is hepatocellular carcinoma.