GLA and Fabry disease: Fabry disease (FD) is a rare lysosomal storage disorder caused by any of several hundred variants of the X‐chromosomal GLA gene, which results in functional deficiency of the lysosomal enzyme α‐galactosidase A (α‐Gal A) and progressive accumulation of glycosphingolipids, particularly globotriaosylceramide (GL‐3), in diverse cell types throughout the body.1