NRP1 has been implicated in diseases characterized by deregulated vasculature such as cancer (Ellis, 2006; Rizzolio & Tamagnone, 2011; Jubb et al,2012; Prud'homme & Glinka, 2012; Chaudhary et al,2014), and in diseases of the retina such as proliferative diabetic retinopathy (Dejda et al,2014), diabetic macular edema (Cerani et al,2013; Sodhi et al,2019) and retinopathy of prematurity (Joyal et al,2011; Dejda et al,2014). The gene discussed is NRP1; the disease is diabetic macular edema.