Mean baseline levels of AST and ALT (± SD) in the adolescent, child, and infant/early child groups (56.3 ± 27.3, 80.6 ± 46.4, and 104.4 ± 66.0 IU/L, and 52.0 ± 16.4, 62.9 ± 38.1, 69.4 ± 33.0 IU/L, respectively; values the same in U/L) were elevated relative to normal ranges, consistent with hepatic involvement in ASMD. Here, GPT is linked to anterior segment dysgenesis.