By analysis of a dataset with GC recurrent and metastatic status from Oncomine database, we found GC patients with low Drosha (RNASEN) expression accounted for a large proportion of patients with recurrence (43.75%) (Supplementary Fig. S1A) and metastasis (45.16%) (Supplementary Fig. S1B). The gene discussed is DROSHA; the disease is gastric cancer.