DROSHA and neoplasm: Furthermore, more lung and liver metastases were observed in mice injected with Drosha WT/ABHD16A overexpressing GC cell group compared with the Drosha WT GC cell group (Fig. 5I, Supplementary Fig. S5D left panel), whereas knockdown of Abhd16a in Drosha-knockdown GC cells significantly reduced metastases in mice lung and liver, and administration of lyso-PS for mice injected with Drosha KD/ABHD16A KD cells could partially restore tumor cell metastatic ability to lung and liver (Fig. 5J,K, Supplementary Fig. S5D right panel).