To confirm that the enhanced lyso-PS was induced by miR-4646-5p/ABHD16A axis, we next investigated the lyso-PS concentration in Drosha wild type GC cells with ectopic miR-4646-5p or ectopic Abhd16a (GC/Drosha/miR-4646-5p, and GC/Drosha/ABHD16A), or in Drosha-silenced GC cells with shRNA against miR-4646-5p or shRNA against Abhd16a (GC/Drosha KD/sh-miR-4646-5p, and GC/Drosha KD/sh-ABHD16A). This evidence concerns the gene ABHD16A and gastric cancer.