Hence, IL-1β, IL-3, IL-12p70 and EOTAXIN (CCL11) appeared in our canonical coefficient model as top markers in the discrimination between both ZIKV-exposed groups and uninfected controls, whereas IL-4 and IFN-α2 appeared to be important only in distinction between those without microcephaly vs. controls and IL-17A in microcephalic neonates vs. controls. The gene discussed is IL1B; the disease is microcephaly.