SERPINE1 and neoplasm: Then, we used differential gene analysis to identify differentially expressed genes between the normal and tumor groups, 15 of which had significant differences between the two groups, including NRP1, EMP3, FCGR2A, PLAUR, SERPINA1, SERPINE1, MYH9, S100A11, MVP, RRAS, ITGA5, SLC16A3, EHD2, PLAU, and HK3, and all had a positive correlation (Figure 1B and Table 1).