Inflammatory macrophages (IMΦ; Ly6G−, CD11chi, F4/80hi, CD11b+) were also similar at 4 h pbi for all of the SGD mutants in mock-infected animals (P > 0.05) and were increased by only D39ΔcbiO1 infection at 24 h pbi (P < 0.05) (Fig. 6C). This evidence concerns the gene ITGAM and infection.