This resulted in 17 genes with at least one novel case as potential NDD candidate genes: HNRNPA0, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPF, HNRNPH1, HNRNPH2, HNRNPH3, HNRNPK, HNRNPLL, PTBP2, SYNCRIP, HNRNPR, HNRNPU, HNRNPUL1, and HNRNPUL2 (n = 118 probands; Fig. 1, Additional File 1: Tables S1, S7, S8, and S11). Here, HNRNPH2 is linked to Neurodevelopmental delay.