At 1 h, the expression of Hsp60 protein in pancreatic tissue of AP group is significant lower than that of NS group, and at 3 h, the expression of Hsp60 protein in AP group increased significantly when compared with that at 1 h, and also higher than that of the NS group at 3 h, but at 5 h, it was significantly lower than that of the NS group. The gene discussed is HSPD1; the disease is alkaline phosphatase measurement.