At each time point, both plasma IL-1 and IL-6 levels in AP group were significantly higher than those of NS group (p < 0.05), and the IL-1 levels in HAP group were lower than those of NS group significantly at 1 h and 5 h (Fig. 3a), while the IL-6 levels in HAP group lower than those of NS group significantly at each time point (Fig. 3b). This evidence concerns the gene IL6 and alkaline phosphatase measurement.