Similarly, dual sero-positivity to E. coli and ETBF was lower in CRC cases of our study (IgA: 5%, IgG: 12%) than reported in Dejea et al. (2018), albeit for CRC patients with FAP (52%).21 One must consider that serology is an indirect and systemic measure of infections. Here, CD79A is linked to colorectal carcinoma.