Upon triggering an enrichment analysis with miEAA 2.0, we find 1,790 affected categories comprising known dementia and Alzheimer's disease related pathways such as the positive regulation of endoplasmic reticulum unfolded protein response (FDR adjusted P-value of 0.003, (50)) and Rab GTPase binding (FDR adjusted P-value 0.001, (51)). Here, RAB6A is linked to early-onset autosomal dominant Alzheimer disease.