Therefore, we compared DEGs (false discovery rate [FDR] < 0.1) in human embryonic stem cells from individuals with HD (carrying 40–48 CAG repeats) with healthy embryonic stem cells that have been differentiated into either CD140+ oligodendrocyte progenitor cells (OPCs) or CD44+ astrocyte progenitor cells (APCs) (Osipovitch et al., 2019). This evidence concerns the gene CD44 and Huntington disease.