Indeed, a recent study investigated the role of milk SIgA in the development of NEC and found a decrease in IgA-bound bacteria and an increase in the Gammaproteobacteria member Enterobacteriaceae in the IgA-unbound fraction of infants who developed NEC.5 This indicated an impaired ability of IgA to bind to Gammaproteobacteria in these infants. Here, CD79A is linked to necrotizing enterocolitis.