We did not observe significant differences in tumor cell proliferation or apoptosis between vehicle and ALW‐treated bone lesions (55.2% ± 2.7% Ki67+ nuclei vector vs 52.2% ± 3.1% Ki67+ nuclei ALW; p = 0.47 Mann–Whitney test; 0.68% ± 0.12% cleaved caspase 3+ nuclei vector vs 1.2% ± 0.24% cleaved caspase 3+ nuclei ALW; p = 0.20 Mann–Whitney test). Here, MKI67 is linked to neoplasm.