The differentially expressed genes (DEGs) in HNSCC were identified from the GSE108061 dataset retrieved from the Gene Expression Omnibus (GEO) database (https://www.ncbi.nlm.nih.gov/gds), which revealed that HOXA10 was significantly upregulated gene in HNSCC (Figure 1A). Here, HOXA10 is linked to head and neck squamous cell carcinoma.