HOXA10 and head and neck squamous cell carcinoma: To explore how LINC0046 enhanced the chemotherapy resistance of HNSCC cells to cisplatin based on the regulatory mechanism, we constructed pcDNA-LINC00461 + miR-195 mimic, siLINC00461 + miR-195-inhibitor, pcDNA-LINC00461 + si-HOXA10, or miR-195 mimic + si-HOXA10 in the FADU/DP cells.