There's still no evidence whether ALOX12 can affect the survival time of OC patients, but in other tumors, such as breast cancer(Huang et al., 2019) and colon cancer(Holzner et al., 2018), down-regulation of ALOX12 could inhibit the invasive ability and enhance the chemosensitivity of tumor cells. Here, ALOX12 is linked to malignant colon neoplasm.