MiR-205 can suppress AR expression by binding to AR 3′ UTR, and also interfere with MAPK and IL-6 signaling pathways in PCa cells (Boll et al., 2013; Hagman et al., 2013), while the promoter region of the miR-205 gene contains ARE and the expression of miR-205 is increased after AR activation by R1881 treatment (Hagman et al., 2013). The gene discussed is AR; the disease is posterior cortical atrophy.