It also promotes malignant behaviors including tumor cell growth, migration, invasion, EMT, angiogenesis, and treatment resistance through mechanisms like C-X-C Motif Chemokine Ligand 16 (CXCL16) and T cell response regulation (Ajona et al., 2018; Mastellos et al., 2018; Medler et al., 2018; Wang et al., 2019). Here, CXCL16 is linked to neoplasm.