CD35 is highly expressed in follicular dendritic cell sarcoma, malignant endometrioma, leukemia, bladder cancer, and nasopharyngeal carcinoma; its high expression in nasopharyngeal carcinoma patients indicates a poor prognosis (Murray et al., 2000; Srivastava and Mittal, 2009; He et al., 2012). This evidence concerns the gene CR1 and nasopharyngeal carcinoma.