AHCY and infection: In vivo efficacy of AHCY inhibitors is remarkable, as a single dose of either of the three distinct AHCY inhibitors 3-deazaneplanocin A, 3-deazaaristeromycin, or 3-deazaadenosine protects mice against a lethal infection of the Ebola virus (subtype Zaire) (Huggins et al., 1999; Bray et al., 2000, 2002).