STING1 and Sepsis: Previous studies demonstrated that lipopolysaccharide (LPS) or stimulator of interferon genes (STING) were closely implicated in sepsis-induced cardiac dysfunction by causing apoptosis, autophagy, pyroptosis, or cardiomyocytes necroptosis (Suzuki et al., 2003; Wang et al., 2015; Sun et al., 2018a; Li N. et al., 2019).