The markedly increased protein expression of MST1, p-LATS1, p-YAP, and YAP (cytoplasm) and the significantly decreased expression of HIF-1α, TAZ, YAP (cells), and YAP (nucleus) in the tumor tissues of the sh-GHET1 group were compared with those of the sh-NC group. The gene discussed is MST1; the disease is neoplasm.