CHD7 and central nervous system cancer: In the same article, Boyd et al. (2019) profiled the transcriptome of CHD7-depleted cells and observed a decreased expression of SEMA3D, a previously identified anti-angiogenetic factor (Sabag et al., 2012), in contrast with increased levels of SEMA4A and SEMA3C, which is positively associated with glioma malignancy (Vaitkiene et al., 2015).