In the same article, Boyd et al. (2019) profiled the transcriptome of CHD7-depleted cells and observed a decreased expression of SEMA3D, a previously identified anti-angiogenetic factor (Sabag et al., 2012), in contrast with increased levels of SEMA4A and SEMA3C, which is positively associated with glioma malignancy (Vaitkiene et al., 2015). Here, CHD7 is linked to glioma.