This showed that the ACO group not only reflected the high expression of cytokines and the interaction between cytokines and receptors in asthma and COPD groups, but also had the characteristics of NLR and P53 of asthma, the cell adhesion, and Fcγ characteristics of COPD and specifically activate antigen presentation, cell migration, and Fcε pathway. The gene discussed is FECH; the disease is chronic obstructive pulmonary disease.