In addition, loss of expression of a LUZP1-interacting tumor suppressor protein named EPLIN (also known as LIM Domain And Actin Binding 1, LIMA1) has been associated with cancer by affecting cancer cell adhesion and migration, and increasing metastatic potential (Jiang et al., 2008; Sanders et al., 2010; Zhang et al., 2011; Liu et al., 2012; Collins et al., 2018). Here, TCHP is linked to cancer.