CML is characterized by chromosomal translocation of “breakpoint cluster region, bcr” and “Abelson, abl” gene sequences from chromosomes 22 and 9, respectively, t(9;22)(q34;q11.2), well known as Philadelphia (Ph) translocation or Ph chromosome (Nowell and Hungerford, 1960). Here, BCR is linked to chronic myelogenous leukemia, BCR-ABL1 positive.