The exogenous transfection of lncRNA H19 overexpression vector to Propofol-exo can inhibit the expression of miR-520a-3p in HCC cells, so as to activate the expression of the downstream target oncogene LIM domain kinase 1 (LIMK1) and destroy the antagonistic effect of Propofol on the malignant biological behaviors of tumor cells (113). The gene discussed is LIMK1; the disease is hepatocellular carcinoma.