NFATC1 and diffuse large B-cell lymphoma: First, NFAT2 could be detected by IHC in lymphoid cells in routine biopsies of several hematologic malignancies, while nuclear NFAT2 was observed in a proportion of Burkitt and diffuse large B cell lymphoma (DLBCL) samples, suggesting an ongoing activation of the pathway in this type of lymphoma (46).