Because of the abnormal protein level of p53/p21WAF1/CIP1 in SW480 and SW620 cells, the mutational status of TP53 in CRC cell lines was assessed as in previous studies (57, 67) and the CCLE database (https://xenabrowser.net/heatmap/) (Figure 7A). Here, CDKN1A is linked to colorectal carcinoma.