ARHGDIB and breast cancer: Few studies show that microRNA (miRNA) 516a exerts carcinogenic effects in BC by attenuating beclin-1 (BECN1)-dependent autophagy (14), the miR-139-5p/Bmi-1 axis is closely related to AMP activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) pathway-dependent autophagy in human BC cells (15), and autophagy-related gene 7 (ATG7) promotes the invasion of BC via an autophagy-mediated increase in the rho GDP dissociation inhibitor beta (ARHGDIB) messenger RNA (mRNA) stability (16).