FOXC2 and gastric cancer: To this end, we co-transfected the miR-4700-3p mimic with a FOXC2 construct lacking its 3’-UTR into MDR cells and observed that FOXC2 co-transfection significantly abrogated the decreased drug resistance induced by ectopic miR-4700-3p expression (Figures 5E, F and Supplementary Figure 3C), suggesting that FOXC2 is the functional target of miR-4700-3p in the MDR phenotype of GC cells.