To investigate the roles of FENDRR in GC chemoresistance, we silenced FENDRR expression with three siRNAs targeting FENDRR in SGC7901/ADR and SGC7901/VCR cells and established stable cell lines infected with FENDRR shRNA lentivirus (shFENDRR) based on the most efficient siRNA sequence (Supplementary Figure 1A). This evidence concerns the gene FENDRR and gastric cancer.