Lin et al. used zebrafish to experimentally validate subgroup-specific enhancers in medulloblastoma (13), Modzelewska et al. used tumors grown in zebrafish to demonstrate that MEK inhibitors can reverse the growth of embryonal brain tumors derived from oligoneural precursor cells (14) and Idilli et al. used them to study telomere maintenance mechanisms in pediatric brain tumors (136). The gene discussed is MAP2K7; the disease is brain neoplasm.